Influence of cellulose ether polymers on ketoprofen release from hydrophilic matrix tablets

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Formulation of Sustained Release Metformin Hydrochloride Matrix Tablets: Influence of Hydrophilic Polymers on the Release Rate And In Vitro Evaluation

Metformin HCL, the only available biguanide, remains the first line drug therapy for patients with Type 2 diabetes mellitus acts by decreasing hepatic glucose output and peripheral insulin resistance. It has relatively short plasma half life, low absolute bioavailability. The overall objective of the present work was to develop an oral sustained release metformin tablet prepared by direct compr...

متن کامل

Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets

The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. The characterization of physical mixture of drug and organic acids was performed by Infra-red spectroscopy. An organic acid was incorporated to set up a system bringing about grad...

متن کامل

Influence of different polymer types on the overall release mechanism in hydrophilic matrix tablets.

The effect of three different types of polymer chain structures on the polymer release from hydrophilic matrix tablets was investigated by comparing a synthetic semi-crystalline linear polymer (PEO), a branched amorphous polysaccharide (dextran) and an amorphous substituted cellulose derivative (HPMC). The polymer release rates for tablets containing mixtures of high and low molecular weight gr...

متن کامل

The Effect of HLB on the Release Profile of Atenolol from Ethyl Cellulose-coated Tablets

It is possible to alter the permeability of ethyl cellulose membrane with certain materials such as surfactants. In this study the effect of surfactant concentration and different HLB values on the release rate of atenolol from ethyl cellulose-coated tablets was evaluated. The results showed that when the concentration of surfactant increased, the rate of drug release also increased. The kineti...

متن کامل

The Effect of HLB on the Release Profile of Atenolol from Ethyl Cellulose-coated Tablets

It is possible to alter the permeability of ethyl cellulose membrane with certain materials such as surfactants. In this study the effect of surfactant concentration and different HLB values on the release rate of atenolol from ethyl cellulose-coated tablets was evaluated. The results showed that when the concentration of surfactant increased, the rate of drug release also increased. The kineti...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: European Journal of Pharmaceutics and Biopharmaceutics

سال: 2004

ISSN: 0939-6411

DOI: 10.1016/j.ejpb.2004.03.006